Why the study?
Does the combination of ACE gene DD genotype and ATRG C allele worsen survival in patients with idiopathic heart failure?
Does the combination of ACE gene DD genotype and ATRG C allele worsen survival in patients with idiopathic heart failure?
The combination of the ACE gene DD genotype and a C allele in the ATRG is associated with worse long-term survival and disease severity in patients with idiopathic heart failure.
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May not yet guide management in idiopathic HF; leaves open prospective validation of genotype-based risk stratification.
Andersson et al. (1999) studied this question.
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