Why the study?
Are ACE, AT1R, and AGT gene polymorphisms associated with an increased risk of coronary artery disease in an Italian population?
Population
414 subjects (205 consecutive coronary artery disease patients and 209 controls) from an Italian population
Comparison
Presence of ACE, AT1R, and AGT gene polymorphisms vs Absence of these specific genotypes / healthy…
Design
Case-control
Authors
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ACE DD and AT1R CC genotypes were associated with CAD; hypothesis-generating for genetic risk assessment in Italians and requires prospective validation.
Are ACE, AT1R, and AGT gene polymorphisms associated with an increased risk of coronary artery disease in an Italian population?
The study identifies ACE DD and AT1R CC genotypes as independent genetic risk factors for coronary artery disease in an Italian cohort.
Cinzia Fatini (2000) studied this question.
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