Key result
Nocturnal hypertension, nighttime systolic pressure, and blunted heart rate variability were associated with increased white matter hyperintensity scores in patients with Parkinson disease.
Why the study?
Are circadian changes in blood pressure and heart rate associated with increased white matter hyperintensities in patients with Parkinson disease?
Population
Patients with Parkinson disease (PD)
Design
Cross-sectional
Authors
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May support nocturnal BP monitoring in Parkinson disease; hypothesis-generating for circadian autonomic roles in cerebral small vessel disease.
Observational
Are circadian changes in blood pressure and heart rate associated with increased white matter hyperintensities in patients with Parkinson disease?
Nocturnal hypertension and circadian autonomic dysfunction are associated with increased white matter hyperintensities in patients with Parkinson disease, highlighting the potential importance of monitoring nocturnal blood pressure to protect against vascular brain damage.
Oh et al. (2013) conducted an observational in Parkinson disease. Nocturnal hypertension and circadian autonomic dysfunction was evaluated on White matter hyperintensities (WMHs) score. Nocturnal hypertension, nighttime systolic pressure, and blunted heart rate variability were associated with increased white matter hyperintensity scores in patients with Parkinson disease.
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