Key result
Night-time systolic blood pressure ≥125 mmHg was associated with significantly greater cerebral white matter hyperintensity volumes compared to <125 mmHg (9.0 vs 4.1 mL, P=0.015).
Why the study?
Does higher night-time systolic blood pressure increase cerebral white matter hyperintensity volume in elderly hypertensive patients?
Observational (n=84)
Does higher night-time systolic blood pressure increase cerebral white matter hyperintensity volume in elderly hypertensive patients?
Absolute Event Rate: 9% vs 4.1%
p-value: p=0.015
Elevated night-time systolic blood pressure (≥125 mmHg) is associated with significantly greater cerebral white matter hyperintensity volumes in elderly hypertensive patients, highlighting the importance of ambulatory blood pressure monitoring.
No takes yet. Share an insight, caveat, or question.
Nocturnal BP parameters may predict WMH progression despite controlled office BP; leaves open whether ABPM-guided targets slow WMH in elderly hypertension.
Kokubo et al. (2015) conducted an observational in Hypertension (n=84). Night-time systolic blood pressure ≥125 mmHg vs. Night-time systolic blood pressure <125 mmHg was evaluated on Cerebral white matter hyperintensity (WMH) volume (p=0.015). Night-time systolic blood pressure ≥125 mmHg was associated with significantly greater cerebral white matter hyperintensity volumes compared to <125 mmHg (9.0 vs 4.1 mL, P=0.015).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: