Why the study?
Do therapeutic doses of digitalis or g-strophanthin alter the T wave and degree of contraction in dogs and cats?
Population
Dogs (n=30) and cats (n=14) anesthetized with ether, with chest opened in the median line.
Design
Preclinical
Authors
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Therapeutic doses alter T waves and contraction in animal models; leaves open translation to human ECG monitoring or dosing.
Do therapeutic doses of digitalis or g-strophanthin alter the T wave and degree of contraction in dogs and cats?
This preclinical study investigates the physiological effects of therapeutic doses of digitalis and g-strophanthin on cardiac contraction and ECG T waves in animal models.
Cohn et al. (1920) studied this question.
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