October 5, 2015BMC Public HealthOpen Access

Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults

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Population

76 healthy black South African young adults aged 18-19 years participating in the Birth to Twenty Cohort…

Design

Cross-sectional

Authors

EREmanuella De Lucia RolfeUniversity of Cambridge KOKen K. OngUniversity of Cambridge ASAlison SleighUniversity of Cambridge

Discussion

Member takes

Implication

SCAT may merit attention in metabolic risk assessment for young black men; leaves open causality, generalizability, and prospective outcomes.

Structured PICO

Population

76 healthy black South African young adults (36 men; 40 women) aged 18-19 years participating in the Birth to Twenty Cohort Study.

Outcome

Associations between specific abdominal fat depots (visceral adipose tissue and subcutaneous-abdominal adipose tissue), insulin sensitivity (HOMA-IR), and metabolic syndrome risk scoresurrogate

In young black South African adults, subcutaneous abdominal adipose tissue appears to be more strongly associated with metabolic syndrome traits and insulin resistance than visceral adipose tissue, particularly in men.

Limitations

Cross-sectional analysis cannot exclude reverse-causality
Young population with majority having healthy range BMI values
VAT and SCAT quantified from only a single MRI slice
Unable to distinguish effects of deep and superficial SCAT due to co-linearity
Unable to differentiate between effects of abdominal SCAT and total fat mass
Did not adjust or stratify for physical activity, diet, early life factors, and social factors

Cite This Study

Rolfe et al. (2015) studied this question.

synapsesocial.com/papers/6a2024c4eaa49a33b5fbf5ed https://doi.org/10.1186/s12889-015-2147-x

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Implication

SCAT may merit attention in metabolic risk assessment for young black men; leaves open causality, generalizability, and prospective outcomes.

Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider