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June 1, 1986CirculationOpen Access

Dynamics of oxygen uptake during exercise in adults with cyanotic congenital heart disease.

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Authors

KSKathy E. SietsemaThe Lundquist InstituteDCDan M. CooperChildren's Hospital of Orange CountyJPJoseph K. PerloffAdult Congenital Heart Disease

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Implication

Randomized trial measures oxygen uptake responses in adults with cyanotic congenital heart disease, indicating impaired pulmonary function.

Key Points

  • This study aims to evaluate how exercise affects oxygen uptake in adults with cyanotic congenital heart disease.
  • Measured VO2 breath-by-breath during exercise transitions in 13 adults with cyanotic congenital heart disease and 9 normal subjects.
  • Analyzed the change in VO2 during the first 20 seconds of exercise and phase II responses.
  • Compared the results of VO2 kinetics between both populations.
  • Phase I VO2 increase in patients was 14.8 +/- 10.9 ml compared to 49.8 +/- 19.2 ml in normals (p < 0.001).
  • The correlation was found between patients' phase I responses and their reported physical activity tolerance (p < 0.01).
  • Phase II VO2 half-time was prolonged in patients: 63 +/- 13 sec vs 15 +/- 13 sec in normals (p < 0.001).

Cite This Study

Sietsema et al. (1986) studied this question.

synapsesocial.com/papers/6a203b89cb26ec8ce28fd3c6https://doi.org/10.1161/01.cir.73.6.1137
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Also Consider

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