Why the study?
Does aortic knob width on chest radiography predict central hemodynamics in patients with known or suspected coronary artery disease?
Does aortic knob width on chest radiography predict central hemodynamics in patients with known or suspected coronary artery disease?
Larger aortic knob width on chest radiography is an independent predictor of increased central systolic blood pressure, offering a simple non-invasive marker for central hemodynamics.
Aortic knob width may indicate central hemodynamics on routine chest radiography; leaves open prospective validation for CAD risk stratification.
BACKGROUND: Aortic knob width on chest radiography is independently related to cardiovascular disease. However, little is known about the correlation between aortic knob width and central hemodynamics. METHODS: Central blood pressure was measured invasively with diagnostic catheter in 92 patients with known or suspected coronary artery disease. RESULTS: Aortic knob width was positively associated with age (r = 0.42; p < 0.001), central systolic blood pressure (r = 0.35; p < 0.001) and central pulse pressure (r = 0.34; p < 0.001). Multivariate analysis showed that larger aortic knob width was independently related to the higher central systolic blood pressure. CONCLUSIONS: Lager aortic knob width on chest radiography is an independent predictor of increase of central systolic blood pressure.
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Higaki et al. (2015) studied this question.
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