Key result
Acute cigarette smoking increased the augmentation index (+7.2% vs +4.4%; P=0.03) and carotid-femoral pulse wave velocity (+1.1 vs +0.6 m/s; P<0.01) more in Black smokers than in White smokers.
Why the study?
Does cigarette smoking increase arterial stiffness and wave reflection more in Black smokers compared to White smokers?
Population
60 smokers (30 Black, 30 White) matched for age, gender, body mass index, and height.
Comparison
Cigarette smoking vs Baseline measurements before smoking, and sham…
Design
Cohort
Follow-up
Acute (immediately after smoking)
Authors
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Greater acute vascular effects of smoking in Black vs White smokers; hypothesis-generating for racial disparities in smoking-related risk.
Observational (n=60)
Does cigarette smoking increase arterial stiffness and wave reflection more in Black smokers compared to White smokers?
Absolute Event Rate: 7.2% vs 4.4%
p-value: p=0.03
Cigarette smoking acutely increases arterial stiffness and wave reflection significantly more in Black smokers than in White smokers, potentially due to differences in nicotine metabolism.
Lemogoum et al. (2006) conducted an observational in Smokers (n=60). Cigarette smoking vs. White smokers was evaluated on Increase in augmentation index (AI) adjusted for heart rate (p=0.03). Acute cigarette smoking increased the augmentation index (+7.2% vs +4.4%; P=0.03) and carotid-femoral pulse wave velocity (+1.1 vs +0.6 m/s; P<0.01) more in Black smokers than in White smokers.
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