Key result
Moderate-load resistance training increases carotid-femoral PWV by ~14% versus high-load training.
Why the study?
The study sought to compare the acute effects of moderate versus high loading intensity resistance training, with the same intensity of effort, on arterial stiffness and wave reflection in young healthy adults.
Does moderate load resistance training compared to high load resistance training acutely increase arterial stiffness and wave reflection in healthy adults?
RCT (n=11)
Randomized order
Does moderate load resistance training compared to high load resistance training acutely increase arterial stiffness and wave reflection in healthy adults?
p-value: p=< 0.05
An acute bout of resistance training to volitional failure using lower loads and higher repetitions imposes a greater workload on the arterial system, evidenced by increased arterial stiffness, compared to heavier loads with lower repetitions.
Moderate-load resistance training acutely increases arterial stiffness more than high-load; extends evidence that repetition/load variables differentially affect acute vascular responses in healthy adults.
This study compared the acute effects of resistance training (RT) between a moderate (ML) and a high loading (HL) intensity (12RM vs. 4RM, respectively), with the same intensity of effort on arterial stiffness and wave reflection in young healthy adults. Eleven healthy adults (age 36.4 ± 6.8 years) performed two RT protocols, ML and HL, in a randomized order. Both RT sessions consisted of three sets of deadlifts and three sets of bench presses, with 2 min rest between sets and exercises. Loading intensity was 12RM and 4RM for the ML and HL conditions, respectively. Measurements of pulse wave velocity (PWV) and pulse wave analysis (PWA; e.g., augmentation index) were collected at baseline, immediately post, and 15 min post-training. ML elicited significantly greater increases in carotid-femoral PWV (from 6.4 ± 0.3 to 7.3 ± 0.5), and augmentation index normalized to 75 bpm (from -5.1 ± 1.1) than HL (all p < 0.05). These findings demonstrate that an acute bout of RT performed to volitional failure using lower loads and higher repetitions impose a greater workload on the arterial and cardiovascular system in comparison to a RT scheme with heavier loads and lower repetitions.
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Karanasios et al. (2025) conducted an RCT in Healthy (n=11). Moderate load resistance training vs. High load resistance training (4RM) was evaluated on Carotid-femoral pulse wave velocity and augmentation index (p=< 0.05). Moderate load resistance training (12RM) elicited significantly greater increases in carotid-femoral pulse wave velocity (from 6.4 to 7.3) compared to high load training (4RM) (p < 0.05).
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