Long-term prognosis analysis of PARACHUTE device implantation in patients with ischemic heart failure: a single-center experience of Chinese patients

Figures

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  Fig. 1. Disposition of subjects enrolled. Six post-myocardial infarction eligible subjects with aneurysm received the PARACHUTE device

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  Fig. 2. Sequence of the PARACHUTE device implantation in the left ventricle. The operation was performed through the femoral artery (a). LV angiography was executed to observe the systolic (b) and diastolic (c) LV geometry. The device was placed in contact within the LV apical wall (d). After balloon inflation to facilitate device expansion, the LV geometric reconfiguration was evaluated in the systolic (e) and diastolic (f) phases. The white dotted line indicates the outline of the chamber morphological characteristics before the device implantation. The white arrow indicates the implanted PARACHUTE device

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  Fig. 3. Cumulative incidence of cardiovascular events in PARACHUTE-implanted patients. a Cumulative event rates for the composite of cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, coronary revascularization, or heart failure end-point. b, c, and d Cumulative myocardial infarction, hospitalization, and mortality, respectively. e Changes in functional capacity according to NYHA. MACEs, major adverse cardiovascular events; MI, myocardial infarction; HFH, hospitalization for heart failure. NYHA, New York Heart Association class

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  Fig. 4. Transthoracic echocardiograph-based cardiac function assessment. Transthoracic echocardiography (TTE)-based cardiac function evaluation was performed at baseline (the first time for MI treatment); before the PARACHUTE device procedure; and at 1 week, 6 months, 1 year, 2 years, and 3 years after device implantation. a, c, and e Comparison of each time point for the left ventricular ejection fraction, left ventricular end-diastolic diameter, and estimated pulmonary artery pressure assessment, respectively. b, d, and f Changes in the TTE-based parameter measurement mentioned above. ***: P < 0.001, compared with baseline; ##: P < 0.01, compared with the PARACHUTE procedure; NS: not significant. mm: millimeter

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  Fig. 5. Case with left ventricular thrombus after device implantation by contrast echocardiography. a CT scan right after the PARACHUTE implantation to check potential device-related migration or embolization. b Latest follow-up detected by contrast-enhanced CT. The filling defect appeared in the apical left ventricle. c and d 3D-TTE and 2D-TEE were applied to exclude device migration, respectively. The white arrow indicates the implanted device. e and f Left ventricular thrombus confirmed by LVO and MCE, respectively. The white arrow points to the filling defect-implied LV apical thrombus