Key result
The ACE I/D polymorphism was not associated with baseline exercise capacity or the training effects of a 3-month cardiac rehabilitation program in patients after acute myocardial infarction.
Why the study?
Does ACE genotype affect exercise capacity or the training effect of cardiac rehabilitation in patients after acute myocardial infarction?
Observational (n=168)
No
Does ACE genotype affect exercise capacity or the training effect of cardiac rehabilitation in patients after acute myocardial infarction?
ACE I/D polymorphism does not appear to influence baseline exercise capacity or the training effects of cardiac rehabilitation in patients after acute myocardial infarction.
ACE I/D polymorphism should not guide post-MI rehabilitation expectations; leaves open other genetic or clinical determinants of training response.
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Iwanaga et al. (2005) conducted an observational in Acute myocardial infarction (n=168). ACE I/D polymorphism vs. Between genotype groups (II, ID, DD) was evaluated on Exercise capacity (peak work rate and peak oxygen uptake) at baseline and after 3 months of cardiac rehabilitation. The ACE I/D polymorphism was not associated with baseline exercise capacity or the training effects of a 3-month cardiac rehabilitation program in patients after acute myocardial infarction.
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