Key result
Aspirin use at hospital discharge following unstable angina was associated with lower long-term mortality over a median follow-up of 16.7 years (HR 0.78; 95% CI 0.65-0.93).
Why the study?
Does aspirin use at discharge reduce long-term mortality in patients presenting with unstable angina?
Population
1,628 residents of Olmsted County, Minnesota presenting to local emergency departments with acute chest pain…
Comparison
Aspirin use in-hospital and at discharge vs No aspirin prescribed on discharge
Design
Cohort
Follow-up
median 16.7 years and 7.5 years
Authors
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Should not yet change practice; extends prior trial data to long-term real-world cohort.
Cohort (n=1,628)
Does aspirin use at discharge reduce long-term mortality in patients presenting with unstable angina?
Hazard Ratio: 0.78 (95% CI 0.65–0.93)
Aspirin use at hospital discharge following unstable angina is associated with a significant reduction in long-term all-cause mortality, extending prior trial results to a population-based cohort.
Razzouk et al. (2010) conducted a cohort in Unstable angina (n=1,628). Aspirin use at discharge vs. Not prescribed aspirin on discharge was evaluated on Long-term mortality (HR 0.78, 95% CI 0.65-0.93). Aspirin use at hospital discharge following unstable angina was associated with lower long-term mortality over a median follow-up of 16.7 years (HR 0.78; 95% CI 0.65-0.93).
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