Why the study?
Does tirofiban added to standard medical therapy improve coronary reperfusion in a patient with acute STEMI and heavy thrombus burden unsuitable for PCI?
Does tirofiban added to standard medical therapy improve coronary reperfusion in a patient with acute STEMI and heavy thrombus burden unsuitable for PCI?
Pharmacological treatment with tirofiban successfully achieved coronary reperfusion in an 80-year-old STEMI patient with heavy thrombus burden who was not a candidate for immediate PCI.
Acute ST elevation myocardial infarction is among the most important causes of cardiac mortality and morbidity. An 80-year-old female patient was referred to our emergency department with chest pain. The patient, who had been diagnosed with ST elevation inferior and right myocardial infarction, received coronary angiography under primary conditions. There was an intense and long thrombus in the right coronary artery. Therefore, the patient was not considered for percutaneous coronary intervention. Glycoprotein IIb/IIIa receptor blockers and tirofiban were added to antiaggregant and anticoagulant therapy. 2 days later, control coronary angiography did not show any signs of residual thrombus and lesions. Coronary reperfusion was achieved successfully with pharmacological treatment without the requirement of mechanical reperfusion. The patient was discharged without complications with further instructions to regulate the medical treatment. In this paper, we aim to present a case which we successfully treated through pharmacological treatment without the need for an invasive intervention.
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A 2015 study studied this question.
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