Why the study?
Do changes in work load and heart rate affect mechanical impedance and filling in the isolated right ventricle of the dog heart?
Do changes in work load and heart rate affect mechanical impedance and filling in the isolated right ventricle of the dog heart?
Hemodynamic factors such as work load and heart rate affect the mechanical properties of the right ventricle, with its physical state early in diastole appearing to determine stroke output.
Hemodynamic effects on canine RV impedance leave open translation to human diastolic filling and output; prospective studies needed.
Ventricular filling in the isolated right ventricle was studied. Mechanical impedance of the ventricle was estimated from simultaneous ventricular pressure and inflow measurements. Changes in work load or heart rate were accompanied by reproducible and characteristic changes in impedance and intraventricular pressure-curve contour. These were discussed in relation to changes in ventricular relaxation, elasticity, and viscosity. The right ventricle fills according to a pattern fixed by hemodynamic factors which affect the mechanical properties of the ventricle. The physical state of the ventricle early in diastole appears to be a determinant of stroke output.
No takes yet. Share an insight, caveat, or question.
Buckley et al. (1955) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: