Population
Guinea pig ventricular myocytes
Design
Preclinical
Authors
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Characterizes NCX Ca2+ fluxes in isolated myocytes; leaves open relevance to intact hearts or clinical translation.
The study provides direct recordings of changes in intracellular calcium and membrane currents driven by the electrogenic, voltage-dependent sodium-calcium exchanger in mammalian heart cells.
Barcenas-Ruiz et al. (1987) studied this question.
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