Why the study?
Does immunoglobulin therapy improve survival and suppress myocarditis in a murine coxsackievirus B3 model?
Population
CB3-infected C3H/He mice (murine coxsackievirus B3 myocarditis model)
Comparison
Immunoglobulin 1 g/kg/day intraperitoneally… vs Untreated control mice
Design
Preclinical
Follow-up
2 weeks
Authors
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Should not yet change practice; hypothesis-generating for immunoglobulin in human viral myocarditis.
Does immunoglobulin therapy improve survival and suppress myocarditis in a murine coxsackievirus B3 model?
Immunoglobulin therapy improves survival and suppresses acute coxsackievirus B3 myocarditis in mice by transferring neutralizing antibodies and inducing anti-inflammatory effects.
Takada et al. (1995) studied this question.
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