The Utilization and Interpretation of Cardiac Biomarkers During Pregnancy
Key result
Cardiac biomarkers (natriuretic peptides and troponin) retain their negative predictive value in pregnant individuals with suspected cardiovascular disease.
Why the study?
While cardiac biomarkers are widely used in nonpregnant populations, their behavior during pregnancy is less well understood.
How should cardiac biomarkers (natriuretic peptides and troponin) be utilized and interpreted in pregnant individuals?
Design
Review
Authors
Discussion
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Member takes
Implication
Supports selective use when CVD suspected in pregnancy; extends Level 5 data but leaves prospective validation open.
Structured PICO
How should cardiac biomarkers (natriuretic peptides and troponin) be utilized and interpreted in pregnant individuals?
P
Population
Pregnant individuals, including those with uncomplicated pregnancies and those with pre-existing or suspected cardiovascular disease
E
Exposure
Measurement of cardiac biomarkers (natriuretic peptides and troponin)
Cardiac biomarkers should not be routinely measured in uncomplicated pregnancies but are valuable for their negative predictive value when cardiovascular disease is suspected.
Cite This Study
Sarma et al. (2022) conducted a review in Pregnancy with suspected cardiovascular disease. Cardiac biomarkers (natriuretic peptides and troponin) was evaluated. Cardiac biomarkers (natriuretic peptides and troponin) retain their negative predictive value in pregnant individuals with suspected cardiovascular disease.