Lung function and risk of fatal and non-fatal stroke. The Copenhagen City Heart Study
Why the study?
Does reduced lung function increase the risk of incident and fatal first-ever stroke in adults?
Population
12,878 men and women aged 45-84 years participating in the Copenhagen City Heart Study
Comparison
Reduced lung function vs Higher lung function
Design
Cohort
Follow-up
From 1976-1978 to December 31, 1993
Authors
Discussion
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Member takes
Implication
Reduced FEV1 was associated with incident stroke; leaves open whether it improves risk stratification beyond standard factors.
Structured PICO
Does reduced lung function increase the risk of incident and fatal first-ever stroke in adults?
P
Population
12,878 men and women aged 45-84 years participating in the Copenhagen City Heart Study
I
Intervention
Reduced lung function (measured by forced expiratory volume in one second [FEV1] as percentage of expected)
C
Comparator
Higher lung function (highest vs lowest FEV1 groups)
O
Outcome
Incident and fatal first-ever strokehard clinical
Reduced lung function (FEV1) is an independent predictor of first-time and fatal stroke, suggesting it may serve as a useful clinical risk marker.
Cite This Study
Truelsen et al. (2001) studied this question.