Why the study?
Does aging decrease endothelium-dependent vasodilation and eNOS/SOD-1 expression in skeletal muscle feed arteries?
Does aging decrease endothelium-dependent vasodilation and eNOS/SOD-1 expression in skeletal muscle feed arteries?
Aging induces a muscle-specific impairment of endothelium-dependent vascular function and decreases eNOS and SOD-1 protein expression in soleus feed arteries but not gastrocnemius feed arteries in rats.
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Aging impairs endothelium-dependent dilation selectively in rat soleus feed arteries; hypothesis-generating for muscle-specific vascular changes in human aging.
Woodman et al. (2002) studied this question.
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