Key result
PACs originating from pulmonary veins were associated with higher paroxysmal atrial fibrillation incidence than non-pulmonary veins (44.4% vs 12.5%, P<0.05); catheter ablation yielded high success.
Why the study?
Does catheter ablation eliminate symptomatic, frequent, and drug-refractory premature atrial contractions?
Population
81 patients with symptomatic, frequent, and drug-refractory premature atrial contractions (PACs)
Design
Cohort
Follow-up
median 21.3 ± 14.3 months
Authors
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PV-origin PACs may identify ablation candidates; observational data leaves open randomized confirmation of AF outcomes.
Observational (n=81)
Does catheter ablation eliminate symptomatic, frequent, and drug-refractory premature atrial contractions?
Absolute Event Rate: 44.4% vs 12.5%
p-value: p=<0.05
Catheter ablation is highly effective for eliminating symptomatic, drug-refractory PACs, with PV-origin PACs showing a higher association with paroxysmal atrial fibrillation.
Huang et al. (2018) conducted an observational in Symptomatic, frequent, and drug-refractory premature atrial contractions (n=81). Premature atrial contractions originating from pulmonary veins vs. Premature atrial contractions originating from non-pulmonary veins was evaluated on Paroxysmal atrial fibrillation (p=<0.05). PACs originating from pulmonary veins were associated with higher paroxysmal atrial fibrillation incidence than non-pulmonary veins (44.4% vs 12.5%, P<0.05); catheter ablation yielded high success.
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