What question did this study set out to answer?

The study aims to measure turbulence-related stresses in a porcine bioprosthetic aortic valve to assess potential impacts.

August 1, 1985Journal of Biomechanical Engineering

Turbulent Stresses in the Region of a Hancock Porcine Bioprosthetic Aortic Valve

View Full Paper

Ask AI

Bookmark

Population

In vitro pulse duplicating system with a 29-mm-diameter porcine bioprosthetic valve mounted in the aortic…

Design

Preclinical

Authors

FWF. J. WalburnMiami Heart Research Institute HSHani N. SabbahHeart Failure & Transplant PSPaul D. SteinVascular / Pulmonary Vascular

Discussion

Member takes

Implication

May indicate platelet activation risk in bioprosthetic valves; leaves open clinical thrombosis relevance.

Key Points

The study aims to measure turbulence-related stresses in a porcine bioprosthetic aortic valve to assess potential impacts.
In vitro pulse duplicating system utilized to assess turbulence in a 29-mm Hancock bioprosthetic valve.
Reynolds stresses calculated using velocities from a two-channel laser Doppler anemometer.
Measurements involved varying stroke volumes up to 80 mL.
Maximal instantaneous Reynolds shear stress reached 2500 dynes/cm2, with maximal normal stress at 6800 dynes/cm2.
Averaged shear stress was 38 dynes/cm2, and normal stress was 380 dynes/cm2 during ejection.
Stress levels noted are potentially damaging to platelets, suggesting clinical implications.

Structured PICO

Population

In vitro pulse duplicating system with a 29-mm-diameter porcine bioprosthetic valve (Hancock, Model 242) mounted in the aortic position

Intervention

Measurement of Reynolds stresses using a two channel laser Doppler anemometer at varying stroke volumes

Outcome

Reynolds shear stress and normal stresssurrogate

In vitro testing of a 29-mm Hancock porcine bioprosthetic aortic valve revealed instantaneous Reynolds stresses of magnitudes reported to cause platelet damage.

Cite This Study

Walburn et al. (1985) studied this question.

synapsesocial.com/papers/6a2090226832c8bccb4d1d64 https://doi.org/10.1115/1.3138544

View Full Paper

Ask AI

Bookmark

Turbulent Stresses in the Region of a Hancock Porcine Bioprosthetic Aortic Valve

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Turbulent Stresses in the Region of a Hancock Porcine Bioprosthetic Aortic Valve

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider