October 1, 2002Pacing and Clinical Electrophysiology
The Relative Lymphocyte Count Predicts Death in Patients Receiving Implantable Cardioverter Defibrillators
Why the study?
Does a decreased relative lymphocyte count predict death in patients receiving implantable cardioverter defibrillators?
Population
136 consecutive patients using automatic defibrillators, with a mean ejection fraction of 0.36 +/- 0.17.
Comparison
Decreased relative lymphocyte count (%L < 20.3%) vs Normal relative lymphocyte count
Design
Cohort
Follow-up
29.6 months
Authors
Discussion
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Member takes
Implication
May aid mortality prognostication in ICD patients; hypothesis-generating and requires prospective validation.
Structured PICO
Does a decreased relative lymphocyte count predict death in patients receiving implantable cardioverter defibrillators?
P
Population
136 consecutive patients (81% men; mean age 64 +/- 12 years) using automatic defibrillators, with a mean ejection fraction of 0.36 +/- 0.17.
I
Intervention
Decreased relative lymphocyte count (%L < 20.3%)
C
Comparator
Normal relative lymphocyte count
O
Outcome
Time to death (survival)hard clinical
A decreased relative lymphocyte count is an independent, readily accessible prognostic marker for mortality in patients with implantable cardioverter defibrillators.
Cite This Study
Ommen et al. (2002) studied this question.