Why the study?
Does isoproterenol alter sustained ventricular tachycardia circuits differently during drug-free versus procainamide or quinidine treated states in patients with inducible sustained VT?
Does isoproterenol alter sustained ventricular tachycardia circuits differently during drug-free versus procainamide or quinidine treated states in patients with inducible sustained VT?
Isoproterenol markedly attenuates the slowing of sustained VT induced by procainamide and quinidine, primarily by altering conduction rather than refractoriness.
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Isoproterenol may attenuate class Ia slowing of VT conduction; leaves open effects on inducibility or outcomes.
Markel et al. (1993) studied this question.
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