Why the study?
Can nonlinear mathematical models detect hemodynamic turbulence in vivo in rat carotid arteries with graded stenoses?
Population
20 Wistar male rats undergoing right carotid artery dissection and blood flow measurement
Comparison
Graded stenoses induced by a collar system vs Control conditions (arteries without stenosis)
Design
Preclinical
Authors
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Noninvasive turbulence detection feasible in small stenotic arteries; leaves open clinical translation from this animal model.
Can nonlinear mathematical models detect hemodynamic turbulence in vivo in rat carotid arteries with graded stenoses?
Nonlinear mathematical analysis of flow signals can successfully detect in vivo hemodynamic turbulence in small arteries (<1.5 mm) with graded stenoses.
May et al. (2002) studied this question.
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