Key result
Transcatheter aortic valve implantation demonstrated noninferiority to surgical aortic valve replacement for mortality at 30 days and 1 year in high-risk elderly patients with aortic stenosis.
Why the study?
Does transcatheter aortic valve implantation (TAVI) improve outcomes compared to surgical aortic valve replacement in elderly patients with symptomatic aortic stenosis at high surgical risk?
Population
Elderly patients with symptomatic degenerative aortic stenosis who are at high risk for surgical aortic…
Comparison
Transcatheter aortic valve implantation (TAVI) vs Surgical aortic valve replacement
Design
Review
Follow-up
30 days and 1 year
Authors
Loading...
Supports TAVI consideration in high-risk elderly aortic stenosis; leaves open long-term durability and stroke risk questions.
Does transcatheter aortic valve implantation (TAVI) improve outcomes compared to surgical aortic valve replacement in elderly patients with symptomatic aortic stenosis at high surgical risk?
TAVI is a safe, cost-effective, and noninferior alternative to surgical aortic valve replacement for mortality in high-risk elderly patients with symptomatic aortic stenosis, despite a higher stroke risk.
Duncan et al. (2012) conducted a review in Symptomatic aortic stenosis. Transcatheter aortic valve implantation (TAVI) vs. Surgical aortic valve replacement was evaluated on Mortality at 30 days and 1 year. Transcatheter aortic valve implantation demonstrated noninferiority to surgical aortic valve replacement for mortality at 30 days and 1 year in high-risk elderly patients with aortic stenosis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: