Key result
Transcatheter aortic valve replacement (TAVR) offers a safe and effective therapeutic option for elderly patients with symptomatic severe aortic stenosis who are at high surgical risk.
TAVR offers a safe and effective therapeutic option for elderly patients with severe aortic stenosis who are at high surgical risk or have contraindications to open-heart surgery.
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Supports TAVR in high-risk elderly with severe AS; extends review evidence but leaves open need for prospective confirmation.
Aortic stenosis is the most common native valve disease, affecting up to 5% of the elderly population. Surgical aortic valve replacement reduces symptoms and improves survival, and is the definitive therapy in patients with symptomatic severe aortic stenosis. However, despite the good results of classic surgery, risk is markedly increased in elderly patients with co-morbidities. Transcatheter aortic valve replacement (TAVR) allows implantation of a prosthetic heart valve within the diseased native aortic valve without the need for open heart surgery and cardiopulmonary bypass, offering a new therapeutic option to elderly patients considered at high surgical risk or with contraindications to surgery. To date, several multicenter registries and a randomized trial have confirmed the safety and efficacy of TAVR in those patients. In this chapter, we review the background and clinical applications of TAVR in elderly patients.
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Dimytri et al. (2012) conducted a review in Aortic stenosis. Transcatheter aortic valve replacement (TAVR) was evaluated. Transcatheter aortic valve replacement (TAVR) offers a safe and effective therapeutic option for elderly patients with symptomatic severe aortic stenosis who are at high surgical risk.
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