Key result
This review explores frailty and other elderly risk factors as metrics for improved risk assessment in transcatheter aortic valve replacement decisions for patients with severe aortic stenosis.
This review emphasizes the role of frailty and other geriatric risk factors in improving risk assessment and decision-making for TAVR in older adults with severe aortic stenosis.
TAVR expands options for high-risk severe aortic stenosis patients; leaves open optimal integration of frailty into risk models.
Patients with severe aortic stenosis are commonly elderly and with significant comorbidity. Surgical intervention can improve symptoms and survival in severe aortic stenosis. However, a large proportion of patients do not undergo surgical intervention because they are deemed to be inoperable or too high risk. Over the last decade, transcatheter aortic valve replacement (TAVR) has been developed, providing an effective, less-invasive alternative to open cardiac surgery for inoperable or high-risk patients. The purpose of this review is to provide an overview of risk assessment in TAVR. Specifically, this article reviews the epidemiology of aortic stenosis, describes the risks and benefits of TAVR across multiple outcome measures, explores frailty and other elderly risk factors as metrics for improved risk assessment and discusses the application of improved risk assessment in TAVR decisions.
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Wong et al. (2013) conducted a review in Severe aortic stenosis. Transcatheter aortic valve replacement (TAVR) was evaluated. This review explores frailty and other elderly risk factors as metrics for improved risk assessment in transcatheter aortic valve replacement decisions for patients with severe aortic stenosis.
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