Time-resolved laser-induced fluorescence shows complex exponential decays that may correlate with the ablation of successive arterial wall layers, offering a potential real-time monitoring scheme.
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Hypothesis-generating for fluorescence-guided arterial ablation monitoring; leaves open translation from animal models to clinical use.
The primary goal of this study was to devise an Optical Fiber based monitoring scheme of the arterial wall ablation by the use of laser induced fluorescence. Preliminary results indicate that the time evolution of the fluorescent light follows complex exponential decays. A comparison of the time characteristics of the decays with the findings of other investigators suggests that these decays may be related to the ablation of the successive arterial wall main layers.
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Papazoglou et al. (1989) studied this question.
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