Key result
Near-infrared optical spectroscopy integrated into an RF ablation catheter enabled real-time monitoring of lesion depth, tissue charring, and coagulum formation in an ex-vivo bovine heart model.
Near-infrared light scattering spectroscopy integrated into an RF ablation catheter can provide real-time feedback on lesion depth and detect adverse events like charring or coagulum formation in an ex-vivo bovine heart model.
May enable safer RF ablation via real-time feedback; leaves open in-vivo human validation.
An optical spectroscopy approach is demonstrated allowing for critical parameters during RF ablation of cardiac tissue to be evaluated in real time. The method is based on incorporating in a typical ablation catheter transmitting and receiving fibers that terminate at the tip of the catheter. By analyzing the spectral characteristics of the NIR diffusely reflected light, information is obtained on such parameters as, contact of catheter with the tissue, lesion formation, depth of penetration of the lesion, formation of char and coagulum during the ablation.
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Demos et al. (2008) studied Cardiac arrhythmia (RF ablation). Optical spectroscopy integrated RF ablation catheter was evaluated on Real-time assessment of lesion depth and formation parameters. Near-infrared optical spectroscopy integrated into an RF ablation catheter enabled real-time monitoring of lesion depth, tissue charring, and coagulum formation in an ex-vivo bovine heart model.
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