Key result
Intravenous inotropic agents can acutely increase cardiac output and improve hemodynamics in patients with heart failure, but they do not improve and can actually worsen long-term clinical outcomes.
Why the study?
Do intravenous inotropic agents improve outcomes in patients with heart failure?
Do intravenous inotropic agents improve outcomes in patients with heart failure?
While intravenous inotropes improve cardiac output in heart failure, their prolonged use is limited by an association with increased mortality.
Inotropes are some of the most commonly used drugs in intensive care. However, their value in treating patients with heart failure is limited and prolonged use is associated with an increased mortality. Nevertheless inotropic agents increase cardiac contractility and can improve the cardiac output of patients with heart failure.
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Banner et al. (2008) conducted a review in Heart failure. Intravenous inotropic agents was evaluated. Intravenous inotropic agents can acutely increase cardiac output and improve hemodynamics in patients with heart failure, but they do not improve and can actually worsen long-term clinical outcomes.
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