Population
15 dogs evaluated 7 to 10 days after placement of Ameroid constrictors around the proximal coronary arteries…
Comparison
Pharmacological stress with dipyridamole and… vs Sham dogs (n=4) and baseline resting state
Design
Preclinical
Follow-up
7 to 10 days after constrictor placement
Authors
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Reinforces MBF reserve–function coupling in chronic stenosis; hypothesis-generating for human ischemia assessment.
In chronic coronary stenosis, abnormal resting regional function and stress-induced dysfunction are directly related to the degree of abnormal myocardial blood flow reserve despite normal resting flow.
Bin et al. (2000) studied this question.
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