Why the study?
Does critical coronary stenosis alter myocardial blood flow distribution and regional function during exercise in dogs?
Does critical coronary stenosis alter myocardial blood flow distribution and regional function during exercise in dogs?
Critical coronary stenosis during exercise in dogs causes a transmural 'steal' phenomenon, reducing subendocardial perfusion and severely impairing regional contractile performance despite subepicardial vasodilator reserve.
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May indicate transmural steal during exercise in critical stenosis; leaves open relevance to human ischemia.
Gallagher et al. (1982) studied this question.
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