Key result
Each 1-SD elevation in pulse pressure independently predicted the initiation of dialysis in patients with diabetes (HR 1.54; 95% CI 1.14-2.08).
Why the study?
The incidence and predictors of starting dialysis in patients with diabetes, particularly blood pressure variables, needed to be determined.
Does higher pulse pressure predict the initiation of dialysis in patients with diabetes?
Population
18 935 people with diabetes mellitus aged 19 to 72 years in Japan
Comparison
Blood pressure variables and glycemic values
Design
Nationwide database historical cohort study
Follow-up
Median 5.3 years
Authors
Loading...
May warrant closer renal monitoring in diabetes; leaves open whether pulse pressure modification alters dialysis risk.
Cohort (n=18,935)
Yes
Does higher pulse pressure predict the initiation of dialysis in patients with diabetes?
Hazard Ratio: 1.54 (95% CI 1.14–2.08)
Higher pulse pressure is a potent independent predictor for the initiation of dialysis in Japanese patients with diabetes.
OSAWA et al. (2018) conducted a cohort in Diabetes mellitus (n=18,935). Pulse pressure was evaluated on Initiation of dialysis (HR 1.54, 95% CI 1.14-2.08). Each 1-SD elevation in pulse pressure independently predicted the initiation of dialysis in patients with diabetes (HR 1.54; 95% CI 1.14-2.08).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: