Key result
A 25-year-old woman developed severe, late-onset doxorubicin-associated cardiomyopathy requiring orthotopic heart transplantation years after treatment for childhood osteosarcoma.
Case Report (n=1)
This case highlights late-onset doxorubicin-associated cardiomyopathy presenting as severe heart failure years after childhood chemotherapy, successfully managed with heart transplantation.
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Severe late doxorubicin cardiomyopathy can require transplantation in survivors; this case leaves open optimal lifelong surveillance protocols.
Wagner et al. (2000) conducted a case report in Congestive heart failure (doxorubicin-associated cardiomyopathy) (n=1). Doxorubicin was evaluated. A 25-year-old woman developed severe, late-onset doxorubicin-associated cardiomyopathy requiring orthotopic heart transplantation years after treatment for childhood osteosarcoma.
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