Monitoring Adherence to Medication by Measuring Change in Blood Pressure
Why the study?
Does monitoring change in blood pressure accurately detect early nonadherence to antihypertensive treatment in patients with prior stroke?
Population
3,433 subjects from the PROGRESS trial
Comparison
Change in blood pressure at 3 months vs Change in blood pressure at 3 months
Design
Cohort
Follow-up
3 months
Authors
Discussion
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Member takes
Implication
BP change at 3 months poorly detects nonadherence; leaves open need for validated alternative adherence assessments.
Structured PICO
Does monitoring change in blood pressure accurately detect early nonadherence to antihypertensive treatment in patients with prior stroke?
P
Population
3,433 subjects from the PROGRESS trial (a randomized trial of blood pressure lowering to reduce the risk of recurrent stroke)
I
Intervention
Change in blood pressure at 3 months (adherent group)
C
Comparator
Change in blood pressure at 3 months (nonadherent group)
O
Outcome
Accuracy of blood pressure monitoring for detecting early nonadherence (sensitivity, specificity, and discriminatory power)surrogate
Monitoring blood pressure changes at 3 months is a poor method for detecting nonadherence to antihypertensive therapy, highlighting the need for alternative adherence assessment methods.
Cite This Study
Hayen et al. (2010) studied this question.