Key result
Objective serum screening reveals 68% medication nonadherence in apparent resistant hypertension.
Why the study?
What is the rate of nonadherence and its effect on blood pressure in patients with apparent resistant hypertension?
RCT (n=98)
Open-label
What is the rate of nonadherence and its effect on blood pressure in patients with apparent resistant hypertension?
Objective serum screening reveals that nonadherence is highly prevalent (68%) in apparent resistant hypertension and directly correlates with blood pressure changes.
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Serum screening identifies nonadherence in most apparent resistant hypertension; leaves open whether routine use improves BP outcomes in practice.
Jager et al. (2017) conducted an RCT in apparent resistant hypertension (n=98). renal denervation vs. usual care was evaluated on nonadherence to blood pressure lowering drugs (95% CI 59-78). Objective serum screening revealed that 68% (95% CI 59-78%) of patients with apparent resistant hypertension were nonadherent to their prescribed antihypertensive medications.
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