Key result
In STEMI patients undergoing primary PCI, 45.7% experienced long-term LVEF improvement, with LAD as the culprit vessel significantly reducing the odds of recovery (OR 0.212).
Why the study?
The study was conducted to assess the incidence and predictors of left ventricular function change in patients with STEMI undergoing primary PCI.
Observational (n=186)
No
Odds Ratio: 0.212 (95% CI 0.078–0.578)
p-value: p=0.002
In patients with STEMI undergoing primary PCI, over half experience a decrease in LVEF during long-term follow-up, while recovery can be predicted by lower peak troponin I, non-anterior STEMI, lower baseline LVEF, and no previous MI.
May guide closer LVEF monitoring after anterior STEMI PCI; leaves open prospective validation of recovery predictors.
Aim: The purpose of the study was to assess the incidence and predictors of left ventricular function change in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI. Methods: 312 patients with STEMI who received primary percutaneous coronary intervention (PCI) between January 2015 and December 2016 were consecutively enrolled in this study. Multiple logistic regression analysis was used to evaluate independent predictors of left ventricular ejection fraction (LVEF) improvement after long-term follow-up. Results: We finally analyzed the LVEF change in 186 patients from baseline to follow-up. The mean age was 61.3 ± 12.5 years, with 78.5% being male. The median duration of follow-up after STEMI was 1,021 (389-1,947) days. 54.3% had a decrease in LVEF and 45.7% experienced an improvement in LV function after primary PCI through long-term follow-up. Logistic regression analysis showed lower peak troponin I, non-anterior STEMI, lower baseline LVEF, and no previous myocardial infarction history were independently associated with LVEF improvement. Conclusion: 54.3% of patients with STEMI undergoing primary PCI had a decrease in LVEF during long-term follow-up. LVEF recovery can be predicted by baseline characteristics.
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Liu et al. (2023) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=186). Left anterior descending (LAD) artery as culprit vessel vs. Non-LAD culprit vessel was evaluated on Left ventricular ejection fraction (LVEF) improvement (ΔLVEF > 0) (OR 0.212, 95% CI 0.078-0.578, p=0.002). In STEMI patients undergoing primary PCI, 45.7% experienced long-term LVEF improvement, with LAD as the culprit vessel significantly reducing the odds of recovery (OR 0.212).
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