Why the study?
How do different vasodilators affect relaxant responses in isolated dog coronary arteries of varying sizes compared to mesenteric arteries?
Population
Helical strips of isolated dog coronary arteries of different sizes and mesenteric arteries
Comparison
Vasodilators including nitroglycerin, sodium… vs Comparison between coronary and mesenteric…
Design
Preclinical
Authors
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Regional selectivity in canine arteries is hypothesis-generating; leaves open human coronary vasomotor applicability pending clinical studies.
How do different vasodilators affect relaxant responses in isolated dog coronary arteries of varying sizes compared to mesenteric arteries?
Different vasodilators exhibit regional selectivity in dog coronary and mesenteric arteries, with PGI2, PGE1, and adenosine preferentially dilating distal small coronary arteries.
Miwa et al. (1985) studied this question.
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