Key result
Hyperglycemia-induced oxidative stress and the activation of various intracellular signaling pathways are major contributors to the development and progression of diabetic cardiomyopathy.
This review highlights the role of hyperglycemia-induced oxidative stress and various signaling pathways in the pathogenesis and progression of diabetic cardiomyopathy.
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Does not support practice changes; leaves open targeted interventions against oxidative stress pathways in diabetic cardiomyopathy.
Watanabe et al. (2010) conducted a review in Diabetic cardiomyopathy. Oxidative stress and signaling pathways was evaluated. Hyperglycemia-induced oxidative stress and the activation of various intracellular signaling pathways are major contributors to the development and progression of diabetic cardiomyopathy.
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