Key result
Hypertension with concentric or eccentric hypertrophy is associated with significantly lower left ventricular longitudinal strain across all three myocardial layers compared to normotensive subjects (P < 0.01).
Why the study?
To evaluate left ventricular deformation across different geometric patterns in hypertensive patients with normal left ventricular ejection fraction using speckle tracking echocardiography.
How does left ventricular deformation measured by speckle tracking echocardiography vary across different geometric patterns in hypertensive patients compared to normotensive subjects?
Cross-Sectional (n=130)
No
How does left ventricular deformation measured by speckle tracking echocardiography vary across different geometric patterns in hypertensive patients compared to normotensive subjects?
p-value: p=<0.01
Hypertension alters left ventricular deformation disproportionately across myocardial layers and orientations depending on the specific geometric pattern of remodeling.
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Strain reduction in hypertensive LVH may signal subclinical impairment; leaves open prognostic value and need for longitudinal validation.
Xu et al. (2019) conducted a cross-sectional in Hypertension (n=130). Hypertension vs. Normotensive subjects was evaluated on Left ventricular longitudinal strain across endocardial, middle, and epicardial layers (p=<0.01). Hypertension with concentric or eccentric hypertrophy is associated with significantly lower left ventricular longitudinal strain across all three myocardial layers compared to normotensive subjects (P < 0.01).
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