Prognostic value of pre-dialysis blood pressure and risk threshold on clinical outcomes in hemodialysis patients

Figures

• 

  Figure 1. Multivariable-adjusted restricted cubic spline plots of hazard ratio for all-cause mortality (A) or CV events (B) according to pre-dialysis SBP levels. Solid line represents HR and gray part surrounded by dot lines represents 95% confidence interval. The multivariable-adjusted model was adjusted for age, sex, diabetes mellitus, dialysis vintage, history of cardiovascular events, CTR, BMI, single pool Kt/V, hemoglobin level, serum albumin concentration, serum phosphate concentration, serum total cholesterol concentration, and serum C-reactive protein concentration, and taking antihypertensive drugs. BMI = body mass index, CTR = cardiothoracic ratio, CV = cardiovascular, SBP = systolic blood pressure.

• 

  Figure 2. Multivariable-adjusted restricted cubic spline plots of hazard ratio for all-cause mortality (A) or CV events (B) according to pre-dialysis DBP levels. Solid line represents HR and gray part surrounded by dot lines represents 95% confidence interval. The multivariable-adjusted model was adjusted for age, sex, diabetes mellitus, dialysis vintage, history of cardiovascular events, CTR, BMI, single pool Kt/V, hemoglobin level, serum albumin concentration, serum phosphate concentration, serum total cholesterol concentration, and serum C-reactive protein concentration, and taking antihypertensive drugs. BMI = body mass index, CTR = cardiothoracic ratio, CV = cardiovascular, DBP = diastolic blood pressure.

• 

  Figure 3. Multivariable-adjusted hazard ratio and 95% confidence interval for all-cause mortality (A) or CV events (B) for every 10 mm Hg increase in pre-dialysis SBP levels in subgroups stratified according to baseline characteristics and treatment. The multivariable-adjusted model was adjusted for age, sex, diabetes mellitus, dialysis vintage, history of cardiovascular events, CTR, BMI, single pool Kt/V, hemoglobin level, serum albumin concentration, serum phosphate concentration, serum total cholesterol concentration, and serum C-reactive protein concentration, and taking antihypertensive drugs. Variables relevant to the subgroups were excluded from each model. BMI = body mass index, CTR = cardiothoracic ratio, CV = cardiovascular, SBP = systolic blood pressure.

• 

  Figure 4. Multivariable-adjusted hazard ratio and 95% confidence interval for all-cause mortality (A) or CV events (B) for every 10 mm Hg increase in pre-dialysis DBP levels in subgroups stratified according to baseline characteristics and treatment. The multivariable-adjusted model was adjusted for age, sex, diabetes mellitus, dialysis vintage, history of cardiovascular events, CTR, BMI, single pool Kt/V, hemoglobin level, serum albumin concentration, serum phosphate concentration, serum total cholesterol concentration, and serum C-reactive protein concentration, and taking antihypertensive drugs. Variables relevant to the subgroups were excluded from each model. BMI = body mass index, CTR = cardiothoracic ratio, CV = cardiovascular, DBP = diastolic blood pressure.