Key result
An average postdialysis systolic blood pressure rise of more than 5 mmHg independently predicted a nearly four-fold increased risk of all-cause mortality (HR 3.925) in chronic hemodialysis patients.
Why the study?
Does a postdialysis systolic blood pressure rise predict long-term mortality in chronic hemodialysis patients?
Population
115 prevalent chronic hemodialysis patients
Comparison
Average postdialysis systolic blood pressure… vs Average postdialysis SBP change between -5 to 5…
Design
Cohort
Follow-up
4 years
Authors
Loading...
May flag higher mortality risk in hemodialysis patients; leaves open whether targeted interventions improve outcomes.
Cohort (n=115)
No
Does a postdialysis systolic blood pressure rise predict long-term mortality in chronic hemodialysis patients?
Hazard Ratio: 3.925 (95% CI 1.41–10.846)
p-value: p=0.008
A postdialysis systolic blood pressure rise of >5 mmHg in hemodialysis patients is an independent predictor of 4-year cardiovascular and all-cause mortality, indicating a need for intensive evaluation of cardiac and volume status.
Yang et al. (2012) conducted a cohort in End-stage renal disease on maintenance hemodialysis (n=115). Average postdialysis systolic blood pressure rise > 5 mmHg vs. Average postdialysis SBP change between -5 to 5 mmHg or drop > 5 mmHg was evaluated on All-cause mortality (HR 3.925, 95% CI 1.410-10.846, p=0.008). An average postdialysis systolic blood pressure rise of more than 5 mmHg independently predicted a nearly four-fold increased risk of all-cause mortality (HR 3.925) in chronic hemodialysis patients.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: