Obese individuals had similar cerebral hemodynamics during exercise and recovery compared to healthy controls, but higher systolic blood pressure during exercise (P<0.05).
Cross-Sectional (n=70)
Does fitness status affect cardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals compared to healthy controls?
Higher aerobic fitness in obese individuals appears to preserve cardiac function during exercise and recovery, despite persistently elevated systolic blood pressure compared to healthy controls.
p-value: p=<0.05
The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age-matched healthy controls (AMHC). Fifty-four middle–aged obese (OB) and 16 AMHC were recruited. Maximal cardiopulmonary function (gas exchange analysis), cardiac hemodynamics (impedance cardiography), and left frontal COP (near-infrared spectroscopy: NIRS) were measured continuously during a maximal incremental ergocycle test. During recovery, reoxygenation/perfusion rate (ROPR: oxyhemoglobin: ΔO2Hb, deoxyhemoglobin: ΔHHb and total hemoglobin: ΔtHb; with NIRS) was also measured. Obese participants (OB, n = 54) were divided into two groups according to the median peak: the low-fit obese (LF-OB, n = 27) and the high-fit obese (HF-OB, n = 27). During exercise, end tidal pressure of CO2 (PETCO2), and COP (ΔO2Hb, ΔHHb and ΔtHb) did not differ between groups (OB, LF-OB, HF-OB, AMHC). During recovery, PETCO2 and ROPR (ΔO2Hb, ΔHHb and ΔtHb) were similar between the groups (OB, LF-OB, HF-OB, AMHC). During exercise and recovery, cardiac index was lower (P < 0.05) in LF-OB versus the other two groups (HF-OB, AMHC). As well, systolic blood pressure was higher during exercise in the OB, LF-OB and HF-OB groups versus AMHC (P < 0.05). When compared to AMHC, obese individuals (OB, LF-OB, HF-OB) have a similar cerebral vasoreactivity by CO2 and cerebral hemodynamics during exercise and recovery, but a higher systolic blood pressure during exercise. Higher fitness in obese subjects (HF-OB) seems to preserve their cardiopulmonary and cardiac function during exercise and recovery.
Gayda et al. (2017) conducted a cross-sectional in Obesity (n=70). Obesity and aerobic fitness level vs. Age-matched healthy controls was evaluated on Cardiovascular hemodynamics and cerebral oxygenation/perfusion during and after maximal incremental exercise (p=<0.05). Obese individuals had similar cerebral hemodynamics during exercise and recovery compared to healthy controls, but higher systolic blood pressure during exercise (P<0.05).