Why the study?
Does preoperative oral clonidine reduce anesthetic drug requirements and improve hemodynamic stability in normotensive patients undergoing infrarenal aortic surgery?
Does preoperative oral clonidine reduce anesthetic drug requirements and improve hemodynamic stability in normotensive patients undergoing infrarenal aortic surgery?
Preoperative oral clonidine reduces the need for supplemental droperidol and lowers plasma norepinephrine levels during infrarenal aortic surgery, while modifying heart rate and blood pressure profiles.
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Clonidine premedication reduces droperidol needs and norepinephrine release in aortic surgery; supports perioperative use and extends RCT evidence for alpha-2 agonists.
Engelman et al. (1989) studied this question.
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