Why the study?
Does clonidine reduce anesthetic requirements and improve circulatory stability in hypertensive patients presenting for major vascular surgery?
Population
21 hypertensive patients presenting for aortic surgery
Comparison
Clonidine 6 micro gram/kg per os 120 min before… vs Placebo
Design
RCT, randomized, double-blind
Follow-up
perioperative
Authors
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Supports clonidine premedication to lower anesthetic needs in hypertensive vascular surgery patients; extends alpha-2 agonist evidence perioperatively.
Does clonidine reduce anesthetic requirements and improve circulatory stability in hypertensive patients presenting for major vascular surgery?
Clonidine effectively reduces anesthetic requirements and improves circulatory stability in hypertensive patients undergoing major vascular surgery.
Quintin et al. (1996) studied this question.
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