Why the study?
Does intravenous clonidine reduce sympatico-adrenal activity and arterial hypertension in patients undergoing CABG surgery?
Population
40 patients scheduled for coronary artery by-pass graft surgery (CABG)
Comparison
Intravenous clonidine added to standard anesthesia vs Control group receiving standard anesthesia
Design
Other
Follow-up
90 min after operation
Authors
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Clonidine suppresses catecholamines without mitigating postoperative hypertension after CABG; challenges presumed causal role of sympathetic activation in this setting.
Does intravenous clonidine reduce sympatico-adrenal activity and arterial hypertension in patients undergoing CABG surgery?
Intravenous clonidine effectively attenuates sympatico-adrenal hyperactivity during and after CABG surgery but does not reduce the incidence of postoperative arterial hypertension.
HELBO-HANSEN et al. (1986) studied this question.
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