Simplifications in the synthesis of short oligonucleotide blocks

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Synthesis of Oligoribonucleotides by the H-Phosphonate Approach Using Base Labile 2′-O-Protecting Groups. V. Recent Progress in Development of the Methodother · 1992 · 20 citations
2. 2Synthesis and applications of oligoribonucleotides with selected 2′-O-methylation using the 2′-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl] protecting groupother · 1990 · 55 citations
3. 3A 5′→3′ Phosphoramidite Approach for the Synthesis of Phosphorodiamidate and Thiophosphoramidate Morpholino Oligonucleotides and Their Chimera2024
4. 4Use of a Dihydroxyacetone Derivative as Protecting Reagent to Phosphorylate Oligonucleotides2025
5. 5Efficient and Improved Solution-Phase Synthesis of Modified RNA Dinucleotides: Versatile Synthons in Cap 1 mRNA TherapeuticsOriginal Research · 2022 · 6 citations