November 1, 1992Nucleosides and Nucleotides

Synthesis of Oligoribonucleotides by the H-Phosphonate Approach Using Base Labile 2′-O-Protecting Groups. V. Recent Progress in Development of the Method

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Authors

EREriks RoznersBinghamton University RRRegīna RenhofaLatvian Biomedical Research and Study Centre MPMarina PetrovaRWTH Aachen University

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Implication

May accelerate RNA research in cardiovascular labs; leaves open clinical translation of oligonucleotide therapies.

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Synthesis of oligoribonucleotides using N-isopropoxyacety(phenoxyacetyl)-2′-O-(2-chlorobenzoyl)-5′-O-dimethoxytritylnucleoside H-phosphonate building blocks

Describes a simple and inexpensive chemical synthesis method for oligoribonucleotides.

Cite This Study

Rozners et al. (1992) studied this question.

synapsesocial.com/papers/6a9288696a4f73282e182b0e https://doi.org/10.1080/07328319208021351

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Synthesis of Oligoribonucleotides by the H-Phosphonate Approach Using Base Labile 2′-O-Protecting Groups. V. Recent Progress in Development of the Method

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Synthesis of Oligoribonucleotides by the H-Phosphonate Approach Using Base Labile 2′-O-Protecting Groups. V. Recent Progress in Development of the Method

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider