Why the study?
Does increased arterial wave reflection impair left ventricular relaxation in patients with essential hypertension?
Population
14 subjects: 7 patients with essential hypertension and 7 age-matched normotensive subjects.
Design
Case-control
Authors
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May link early wave reflection to impaired LV relaxation before hypertrophy in hypertension; hypothesis-generating pending prospective confirmation.
Does increased arterial wave reflection impair left ventricular relaxation in patients with essential hypertension?
Early return of enhanced wave reflection in essential hypertension may profoundly impair left ventricular relaxation function even before the development of cardiac hypertrophy.
Chang et al. (1994) studied this question.